New paper in Net Neuro on the reorganization of functional networks across the menstrual cycle

Congratulations to Josh Mueller and Laura Pritschet, co first-authors of a new paper "Dynamic community detection reveals transient reorganization of functional brain networks across a female menstrual cycle" now in press in Network Neuroscience. 

Summary

Sex steroid hormones influence the central nervous system across multiple spatiotemporal scales. Estrogen and progesterone concentrations rise and fall throughout the menstrual cycle, but it remains poorly understood whether day-to-day fluctuations in hormones shape human brain dynamics. Here, we assessed the structure and stability of resting-state brain network connectivity in concordance with serum hormone levels from a female who underwent fMRI and venipuncture for 30 consecutive days. Our results reveal that while network structure is largely stable over the course of a menstrual cycle, temporary reorganization of several large-scale functional brain networks occurs during the ovulatory window. In particular, a default mode subnetwork exhibits increased connectivity with itself and with nodes belonging to the temporoparietal and limbic networks, providing novel perspective into brain-hormone interactions.