Sex steroid hormones exert powerful effects on regions of the mammalian brain that support higher-order cognitive functions. The Jacobs Lab explores the tightly coupled relationship between our endocrine and nervous systems. We use neuroimaging, endocrinology, and computational approaches to decipher how endogenous and exogenous hormone factors (e.g. neuroendocrine aging during menopause, chronic hormone suppression, oral contraceptives, the menstrual cycle) influence brain structure, function, and cognition.
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