Sex steroid hormones regulate cell survival, synaptic plasticity, and global morphology of brain regions that support learning and memory. The Jacobs Lab explores the structural and functional changes in the human brain that occur in response to changing hormonal conditions. We pair brain imaging tools with endocrine assessments to study how endogenous and exogenous hormonal factors (e.g. neuroendocrine aging during menopause, use of hormone-based medications) influence brain structure, function, and cognition.
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