Rodent, non-human primate, and human studies have established the powerful influence sex steroid hormones have on regions of the mammalian brain that support higher level cognitive functions. The Jacobs Lab explores the tightly coupled relationship between our endocrine and nervous systems. We use neuroimaging, endocrinology, and computational approaches to decipher how endogenous and exogenous hormone factors (e.g. neuroendocrine aging during menopause, chronic hormone suppression, the menstrual cycle) influence brain structure, function, and cognition.
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