Credit: Tony Mastres

About Us

Sex steroid hormones regulate cell survival, synaptic plasticity, and the global morphology of brain regions that support learning and memory. The Jacobs Lab explores the structural and functional changes in the human brain that occur in response to changing hormonal conditions. We pair brain imaging tools with endocrine assessments to study how endogenous and exogenous endocrine factors (e.g. neuroendocrine aging during menopause, use of hormone-based medications, and menstrual cycle-dependent changes) influence brain structure, function, and cognition.

Join the Jacobs Lab

Interested in joining the lab?

Help Us Advance Women's Health

Volunteer for a Study The Jacobs Lab is seeking adults (ages 45-60) from the Santa Barbara area to participate in a study of healthy aging. Learn more here and contact us at